One in three of those with diabetes and one in five with hypertension will go on to develop chronic kidney disease (CKD). The total cost of care of CKD can be dramatically reduced when diagnosis and treatment begin during the initial stages of the disease. Employers play a pivotal role in the early detection of CKD by covering and promoting preventive screenings and providing access to interventions to slow disease progression. The important recommendations in this action brief can serve as a starting point for employers to develop and launch impactful initiatives to decrease the impact of CKD on their workforce.