Currently hemophilia treatment is focused on replacement or substitution of clotting factor – having the right amount of factor replacement at the right time for the patient – and patient adherence to a personalized treatment plan. Specialty medication prescriptions used to treat hemophilia are written in a manner that does not follow traditional medication dosing. In addition, pharmacies may dispense extra doses for breakthrough bleeds. If the patient already has extra doses on hand, sending additional doses is wasteful and costly. The management of factor replacement, known as assay management and dose/adherence management, can help to reduce waste and avoid unnecessary health care costs.